gulp-load-plugins simplifies Gulp configuration by automatically loading your Gulp plugins. Instead of manually requiring each plugin individually, it searches your package.json dependencies, loads modules matching gulp-*, and exposes them as properties of a single object. This reduces boilerplate code and streamlines your Gulpfile, making it more readable and maintainable. It automatically camel-cases plugin names, offering a convenient and intuitive way to access them within your Gulp tasks.